Research on C60 and health

Although C60 was isolated several decades ago, research into the effects of the molecule on human health is still in the early stages.

Most studies have been performed in cells or animals, and only a handful of human studies have been done.

The chart below summarizes the current state of the C60 research landscape in seven health and wellness areas. Each field has been given a grade based on the number of studies that showed an effect of C60 and whether they were studied in humans or animals:

  • +: one or more studies in animals have shown an effect
  • ++: one or more studies in humans have shown an effect
  • +/-: multiple studies have shown mixed results



Notable Studies

Skin care


A 2010 randomized, placebo-controlled trialTrusted Source examined the use of a C60-containing skin cream in 23 Japanese women and the effect on wrinkles and skin roughness.

In a small 2011 study, researchers studied the effects of a face gel containing C60 on acne.

Studies done in mice have also examined the ability of C60-containing solutions to block the effects of ultraviolet radiation and promote hair growth when applied to the skin.

Inflammatory conditions


In 2019, research was publishedTrusted Source that examined the effects of a C60 derivative on joint damage and inflammation in rats with arthritis.

A 2016 studyTrusted Source explored the ability of a C60 compound to regulate inflammation in a mouse model of eczema.

Cognitive function


Rat models of amyloidosis and Alzheimer’s disease have been used to examine the effects of C60, delivered directly into the brain, on learning and memoryTrusted Source and cognitive functionTrusted Source.

Cancer, cancer treatment effects


Studies have explored the effects of C60 derivatives on tumor growth, metastasis, and survival in miceTrusted Source and ratsTrusted Source.

A 2020 studyTrusted Source examined the ability of C60 to protect against lung damage in mice treated with bleomycin, an anti-cancer drug.

Muscle fatigue


A 2017 studyTrusted Source explored the effects of C60 on muscle fatigue and endurance in rats.



Researchers in 2012 and in 2020 examined the ability of C60 to affect the lifespan of rats.



Studies in rat models of diabetes have examined the ability of C60 to prevent neuronal and kidney damageTrusted Source resulting from hyperglycemia.

In a 2020 study, researchers explored whether C60 affected the gut microbiome and how that influenced insulin resistance.


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